Building the future of medicine, one data point at a time
Detect and monitor health conditions and changes in physiology using our range of custom biomarkers, all collected via Empatica’s medical-grade wearable sensors.
Pioneering new approaches in clinical trials and healthcare
Empatica’s biomarkers and wearables are already being used in hundreds of studies to continuously collect health information from patients and study participants, and indicate changes in their health status. This information is enabling clinicians, patients and researchers to gain an unprecedented understanding of human health, provide better care, and advance research behind treatments.
Imagine a world where patients don’t have to do the hard work
Remote measurements
Support continuous measurements outside the physical confines of the clinical environment
Less self-reporting
Biomarkers collected using advanced sensors can provide additional accuracy and objective data without burdening the patient with additional self-reports
Complete patient view
Receive an immediate, complete view of every patient’s disease progression and response to treatments
Enhanced care
Custom biomarkers can enable a deeper understanding and improved care for dozens of chronic conditions
We develop accurate physiological and behavioral biomarkers to improve healthcare diagnostics via continuous, passive and unobtrusive health monitoring that fits in everyday life
Vital signs and physiology
Equipped with a custom PPG, EDA sensors, gyroscopes, accelerometers and a peripheral thermometer, our wrist-worn devices have been designed to accurately and objectively observe physiological biomarkers 24 hours a day:
Pulse Rate
Ventral EDA
PRV
Peripheral temperature
Respiration
Oxygen saturation
Our custom biomarkers are built in partnership with some of the world’s top institutions, and are validated in a clinical setting
Convulsive seizures
Uses Electrodermal Activity and motion to automatically detect Generalized Tonic Clonic Seizures (GTCS) and provides insight into autonomic arousal following each seizure event, which has been found to correlate with Post-ictal Generalized EEG Suppression (PGES), an important biomarker for SUDEP.
Activity/motion and EDA changes when a seizure occurs.
Actigraphy-based rest detection
Provides objective measures of rest quality, such as efficiency, fragmentation and movements, within the onset and offset of the identified rest period. Detects the boundaries of periods of rest based on the quantity of movement extracted from the accelerometer sensor.
Fragmentation while a person is resting, quantity of movement extracted from the accelerometer.
Sleep staging
Provides insight into the autonomic activity and brain dynamics during sleep through non-invasive monitoring of physiological signals overnight, and provides an overview on sleep architecture composed by light sleep (NREM 1/2), deep sleep (NREM 3), REM and wake stages.
Brain activity and movement during sleep. An overview of sleep stages.
Validation in collaboration with: Brigham and Women's Hospital Boston (2015- ongoing) Outpatient study 50+ older adults (E4+ PSG).
Boston Children's Hospital (Ongoing) Inpatient study 20+ children (E4 + PSG).
Activity
Detects and analyzes movements to determine physical activity intensity and compute distances covered during daily movements. Automatically recognizes number of steps and distinguishes between low intensity and high intensity activity, such as walking, running or other sports.
Analysis of movement (intensity, duration) while doing physical activity (sports, running, walking, etc).
Stress
Detects autonomic arousal in response to external stimuli and provides insight about the sympathetic nervous system by monitoring EDA and temperature changes/trends/values. Used in collaboration with NEC on a study involving 300 subjects in a large-scale effort to measure and combat stress in the workplace.
Autonomic arousal and temperature responses to external stimuli.
Depression
Provides insight into physiological signals associated with activity, rest, and emotional responses against Hamilton Depression Rating Scale Score (HDRS) changes. Detects both short-term and long-term patterns that enable identifying triggers and provide accurate forecasts for depression. Original research conducted by Empatica’s Chief Scientist Rosalind Picard at MIT with Empatica technology.
Accurate monitoring of changes in gold standard depression scores (HDRS) over a typical 8-week treatment period.
Predicted vs. Actual HDRS vales: Pearson correlation 0.834, p< 0.0001
Suicide
Used in detecting digital phenotypes related to suicidal thoughts, measuring skin conductance levels to assess changes in physiological distress.
Study conducted by Harvard University Clinical Psychologist Dr. Matthew K. Nock involving hundreds of individuals wearing Embrace2.
Influenza forecasting
Monitors activation of the autonomic nervous system together with behavioral patterns to identify pathogen exposures prior to the manifestation of any symptoms. Created in partnership with DRIVeand currently under validation with the collaboration of Duke University and Columbia University.
Integrating with the longitudinal Prometheus project.
Our autonomic measures are relevant to a range of medical conditions that affect the lives of billions
Addiction
Affect dysregulation
Alcoholism
Alzheimer's disease
Anesthesia
Anxiety disorder
Attention deficit and hyperactivity disorder
Autism disorders
Depression
Diabetes
Dialysis
Dysthymia
Endocrine disorders
Epilepsy
Hot flashes
Hypertension
Post-traumatic stress disorder
Quadriplegia
Sensory processing and modulation
Schizophrenia
Sexual dysfunction
Sleep disorders
Oppositional defiant disorder
Stroke
Bipolar disorder
Cystic fibrosis
Dementia
Hypoglicemia
Pain management
Parkinson's disease
Temporary paralysis
Thyroid disfunction
Interested in hearing more about our digital biomarkers, or collaborating on new biomarker development or customization?
Embrace is currently available only in English. Embrace is an investigational device in the USA and a medical device in the EU. If you do not see your country listed, please visit the International site.
Pulse Rate
Ventral EDA
PRV
Peripheral temperature
Respiration
Oxygen saturation
