Hundreds of researchers across fields use the E4 and Empatica’s tools for full access to clinical-quality, real-time biometric data
Exploiting physiological data to detect virtual reality sickness
Researchers at IRT b-com, France, explored the use of physiological signals from noninvasive wearable devices like the E4 to detect virtual reality sickness. Their method involved training Machine Learning models using data from the E4 to detect when participants felt sick while playing video games for 30 minutes, in addition to self-reporting. Results from the study showed up to 91% accuracy in detecting VR sickness when using the E4, paving the way for adapting VR video games to players’ sickness levels using real-time feedback.
Classifying emotions through multimodal signal recordings
Gloria Cosoli and her team at Università Politecnica Delle Marche (Italy) researched the possibility of utilizing data from multiple E4 sensors to identify and classify emotions. Data were recorded from 7 healthy participants at rest, with the participants wearing the Empatica E4 on the dominant wrist while listening to 1-minute audio recordings as stimuli. Results showed up to 75% accuracy across all the evaluation metrics, and the data from the algorithms trained in this research have been validated on a publicly available dataset (WESAD).
Measuring stress intensity through Machine Learning methods
In this study, Pekka Sirtola et al. collected data from the E4, analyzing it using different Machine Learning models to determine the feasibility of detecting and identifying different levels of stress. Participants were asked to drive a car in stress and non-stress situations while wearing the E4, and regression and classification ML models were compared during data analysis. Their results show that regression models outperform classification models in stress detection, and unlike the latter, can also be used to identify different levels of stress.
How Dutch and German visitors experience an exhibit of Second World War stories
Researchers used the social identity theory framework to assess differences in emotional reactions of Dutch and German visitors to stories of the Second World War, as presented at a Dutch museum exhibit. E4 wristbands were worn by visitors to measure emotional reactions using physiological signals of heart rate and heart rate variability, in addition to self-reporting via a tablet-administered intake questionnaire. It was found that patterns in the physiological and self-report data differed, and that generally participants did not simply categorize themselves with either national or human identities of characters based on what their respective stories emphasized.
Exploring play as a healing factor in hospitalized children
Using the Empatica E4 and SDK, researchers at Copenhagen University Hospital developed a method that uses play to help children overcome difficult experiences in a hospital environment. The solution consists of a physical teddy bear and an E4 wristband, connected via a custom-designed tablet/smartphone application with a virtual teddy bear that the child can interact with. The children are asked to act as caregivers for the teddy bear while interacting with the app, and help the teddy bear through the treatment. This shift in focus and perspective for the child increased emotional stability, with a calming effect.
E4 Bytes: Predicting aggressive outbursts in people with autism a minute in advance
Using the E4, Northeastern behavioral scientist Matthew Goodwin and his team have created an algorithm that can predict aggressive outbursts in people with autism by monitoring physiological indicators of stress. By analyzing the changes in physiology that occurred around each episode, the algorithm developed by the researchers could predict an aggressive outburst a minute in advance with 84 percent accuracy. Even a minute's warning can be crucial in helping caregivers prevent an aggressive outburst, showing there is true potential in the use of wearables and AI to alert caregivers and help mitigate their emergence, occurrence, or impact.
Electrophysiological evidence of emotional engagement during a roller-coaster ride with VR Add-On
This research evaluated the methodological feasibility and usefulness of ambulatory recordings of skin conductance (SC) responses during a tourism experience. The goal was to measure emotions accurately while experiences unfolded in time. Skin conductance (SC) was recorded with E4 wristbands in participants while they experienced a roller coaster ride with or without a Virtual Reality (VR) headset. Through the collected data, the researchers found that SC response time series were meaningfully related to the different ride elements, establishing psychophysiological measurements as a new avenue for understanding how hospitality, tourism & leisure experiences dynamically develop over time.
Developing a model to predict migraine attacks using biosignals
Researchers at The University of Oulu used the E4 in a study on the early detection of migraine attacks via human-measured biosignals. The aim was to develop a predictive model that assists individuals in taking their medication on time, preventing painful attacks. The E4 was used to collect sleep data and, altogether, 110 features were extracted from each night’s biosignals, and used to train machine learning models. The experiments showed that early symptoms for migraine are highly personal, and that using personal recognition models the accuracy for detecting attacks one night prior is over 84%.
The detection of fever has played a central part in patient monitoring. Nursing observations are often taken as part of standard vital signs, the frequency depending on patient acuity. However, this is time-consuming and may miss important spikes in temperature suggesting incipient or unrecognized sepsis. In a study conducted at The Royal Melbourne Hospital, the E4 was used to monitor a series of admitted patients. The researchers found that a temperature of 37.5 or more reliably identified patients with infection, concluding that peripheral temperature recording has the potential to provide an early indication for patients with sepsis.
Detecting moments of stress in real-world settings
Researchers at the University of Salzburg, University Hospital Zurich, Harvard University, University of Groningen, and the University of Birmingham, aimed to introduce a new algorithm that leverages the capabilities of wearable physiological sensors to detect moments of stress (MOS). They proposed a rule-based algorithm based on galvanic skin response and skin temperature, which they measured with the E4. The new algorithm combines empirical findings with expert knowledge to ensure transferability between laboratory settings and real-world field studies. Results show that the algorithm detects MOS with 84% accuracy, showing high correlations between measured (by wearable sensors), reported (by questionnaires and eDiary entries), and recorded (by video) stress events.
Wearables and the quantified self: Systematic benchmarking of physiological sensors
Though wearable sensors are increasingly used in research, it is often not clear how accurate their measurements are compared to those from well-calibrated, high-end laboratory equipment. Researchers at the University of Salzburg and Harvard demonstrated an approach to quantify the accuracy of wearables, including the E4, in comparison to laboratory sensors. The benchmarked wearables provided physiological measurements such as heart rate and inter-beat interval with an accuracy close to that of the professional high-end sensor. The accuracy varies more for other parameters, such as galvanic skin response, yet the E4 demonstrated extraordinary stability and high quality throughout.
The E4 is equipped with sensors designed to gather high-quality data. It is the only wearable on the market to combine EDA and PPG sensors, simultaneously enabling the measurement of sympathetic nervous system activity and heart rate.
PPG Sensor
Measures Blood Volume Pulse (BVP), from which heart rate variability can be derived
3-axis Accelerometer
Captures motion-based activity
Event Mark Button
Tag events and link them to physiological signals
EDA Sensor (GSR Sensor)
Measures the constantly fluctuating changes in certain electrical properties of the skin
Infrared Thermopile
Reads peripheral skin temperature
Internal Real-Time Clock
5ppm high accuracy time reference
PPG Sensor
Measures Blood Volume Pulse (BVP), from which heart rate variability can be derived
3-axis Accelerometer
Captures motion-based activity
Event Mark Button
Tag events and link them to physiological signals
EDA Sensor (GSR Sensor)
Measures the constantly fluctuating changes in certain electrical properties of the skin
Infrared Thermopile
Reads peripheral skin temperature
Internal Real-Time Clock
5ppm high accuracy time reference
From laboratory settings to at-home analysis, E4 is the perfect solution
Recording mode
The E4 has an internal memory that allows you to record for up to 60 hours with 5s synchronization resolution. An ideal solution for longitudinal studies.
E4 manager
Imports your data via USB and transfers it to our secure cloud platform. You can also upgrade the Firmware of your E4. Works with Windows and Mac.
E4 connect
View and manage your data on our secure cloud platform. You can also download raw data in CSV format for easy processing and analysis in third party applications. Your data is secured with encryption. Data includes: Electrodermal Activity (EDA) also known as Galvanic Skin Response (GSR), Blood Volume Pulse (BVP), Acceleration, Heart Rate (HR), and Temperature.
Bluetooth® Streaming Mode
View sensor data of the connected device in real time. Data will automatically be uploaded to E4 connect, our secure cloud platform, after the session ends. Ideal for laboratory settings and live events where you want to showcase data.
E4 realtime
The E4 wristband connects to a smartphone or a tablet via Bluetooth® enabling real-time data viewing. Easily zoom and pan to check your signals. Data will automatically be uploaded to E4 Connect after a session ends.
Development tools
Desktop integration
Get real-time signals on your PC. Filter and receive data in a custom format
Mobile API
Develop apps that leverage real-time data from the E4 on Android or iOS
CE Cert. No. 1876/MDD (93/ 42/EEC Directive, Medical Device class 2a)
FCC CFR 47 Part 15b
IC (Industry Canada)
RoHS
MIC Japan: BLE112 has type approval certification ID R209- J00046
Used in over 1,000 studies and trials
Read more about the scientific contributions of Empatica and other international research groups that make use of the E4 wristband across a variety of discoveries.
Read more about the scientific contributions of Empatica and other international research groups that make use of the E4 wristband across a variety of discoveries.
“The E4 demonstrated remarkable stability and quality in the measurement of physiological signals - also in highly mobile settings.”
Pekka Siirtola
Researcher at University of Oulu
“The E4 is the most capable device in the market containing more sensors than any other wrist-worn device.”
Elena Di Lascio
Ph.D. at USI, Lugano
“One of the main advantages of using the E4 is the possibility of gathering high-quality raw sensor data in real-time.”
Matt Goodwin
PhD. Northeastern University
“The E4 makes raw data accessible. It’s not pre-processed with a black box algorithm as is the case with most consumer wearables.”
Embrace is currently available only in English. Embrace is an investigational device in the USA and a medical device in the EU. If you do not see your country listed, please visit the International site.